Luciferin is a common bioluminescent substrate used for imaging and quantification of luciferase expression. It emits a characteristic yellow-green light upon oxidation by luciferase in the presence of cofactors such as ATP, Mg2+ and oxygen.
Catalog number: SL30101
SL30101-100mg - CHF50
SL30101-1g - CHF140
SL30101-5g - CHF500
Luciferase Labelled Cell Lines
We offer light-producing oncology and stem cell lines. Our bioluminescent oncology cell lines cover a wide range of cancer models including breast, colorectal, prostate, lung, lymphoma and many more. These cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP).
The cells are bright enough to measure tumor growth in your in vivo optical imaging system right after injection, way before the tumors are palpable, allowing you to start collecting data at time points impossible with traditional micrometer measurements. All our bioluminescent oncology cell lines meet the highest standards and are confirmed pathogen free.
Bioluminescent Glucose Luciferin (BiGLuc)
Bioluminescent Glucose Luciferin (BiGLuc) is a recently developed bioluminescent glucose-uptake probe for real-time, non-invasive longitudinal imaging of glucose absorption both in vitro and in vivo.
Fatty Acid Luciferin
Fatty Acid Luciferin is a bioactivatable molecular imaging probe for the real-time bioluminescent imaging of fatty acids fluxes in cell culture and living animals. The probe includes luciferin molecule conjugated to a long-chain fatty acid via a cleavable disulfide bond that is stable in the extracellular environment but readily reduces intracellularly by glutathione after lipid uptake. This probe provides noninvasive, real-time, spatiotemporal and quantitative imaging of fatty acid uptake which opens a wide range of opportunities for establishing new drug screens as well as for investigations of fundamental biological processes involving FFA absorption and distribution in living animals.
Hydrogen Peroxide Luciferin
Hydrogen Peroxide Luciferin is a chemoselective bioluminescent probe for the real-time detection of H2O2 in cell culture and living animals. Hydrogen Peroxide Luciferin is a boronic acid-caged firefly luciferin molecule that selectively reacts with H2O2 to release firefly luciferin, which triggers a bioluminescent response in the presence of firefly luciferase. The high sensitivity and selectivity of Hydrogen Peroxide Luciferin for H2O2, combined with the favorable properties of bioluminescence for in vivo imaging, afford a unique technology for real-time detection of basal levels of H2O2 generated in healthy, living mice.
Indocyanine green (ICG) is a near-infrared fluorophore widely used for multiple imaging applications and in medical diagnostics.
We offer ICG NHS ester at an affordable price.
Catalog number: SL30102
SL30102-1mg - CHF150
SL30102-5mg - CHF450
SL30102-25mg - CHF1500
Also available a recently developed Aqua-ICG molecule where ICG dye is chemically protected with small biodegradable molecule. Data Sheet
Fluorescent Imaging Agents
We offer a portfolio of targeted fluorescent imaging reagents for in vivo imaging of various biological processes. The reagents consist of targeted moiety conjugated to near-IR dyes, that possess ideal properties for in vivo use (ex. fluorescently labeled antibodies, peptides, and small molecules).
Lentiviral Luciferase Expressing Constructs
We also offer a panel of mammalian luciferase expressing lentiviral vectors.